Cellosaurus logo
expasy logo

Cellosaurus NP446-cyclinD1-hTert (CVCL_B3Q7)

[Text version]
Cell line name NP446-cyclinD1-hTert
Synonyms NP446Cyclin D1/hTert; NP446-cyclinD-hTert
Accession CVCL_B3Q7
Resource Identification Initiative To cite this cell line use: NP446-cyclinD1-hTert (RRID:CVCL_B3Q7)
Comments Population: Chinese.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1582; CCND1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Pharynx, nasopharynx, epithelium; UBERON=UBERON_0001951.
Cell type: Epithelial cell of nasopharynx; CL=CL_1001573.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B3Q6 ! NP446-CDK4R24C-hTert
Sex of cell Female
Age at sampling 42Y
Category Telomerase immortalized cell line
Publications

PubMed=23161911; DOI=10.1073/pnas.1202637109; PMCID=PMC3528537
Chi-Man Tsang, Yim-Ling Yip, Kwok-Wai Lo, Wen Deng, Ka-Fai To, Pok-Man Hau, Victoria Ming-Yi Lau, Kenzo Takada, Vivian Wai-Yan Lui, Maria Li Lung, Hong-Lin Chen ...Show all 15 authors... , Mu-Sheng Zeng, Jaap Michiel Middeldorp, Annie Lai-Man Cheung, George Sai-Wah Tsao; Show fewer authors
Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cells.
Proc. Natl. Acad. Sci. U.S.A. 109:E3473-E3482(2012)

DOI=10.1016/B978-0-12-814936-2.00005-5
Yim-Ling Yip, Wei-Tao Lin, Wen Deng, Chi-Man Tsang, George Sai-Wah Tsao;
Establishment of nasopharyngeal carcinoma cell lines, patient-derived xenografts, and immortalized nasopharyngeal epithelial cell lines for nasopharyngeal carcinoma and Epstein-Barr virus infection studies.
(In book chapter) Nasopharyngeal carcinoma. From etiology to clinical practice; Lee, Anne Wing-Mui & Lung, Maria Li & Ng, Wai-Tong (eds.); pp.85-107; Academic Press; New York; USA (2019)

Cross-references
Encyclopedic resources Wikidata; Q110433114
Entry history
Entry creation16-Dec-2021
Last entry update14-Aug-2025
Version number7