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Cellosaurus HEK293-MRP7 (CVCL_B3Q1)

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Cell line name HEK293-MRP7
Synonyms HEK293/MRP7
Accession CVCL_B3Q1
Resource Identification Initiative To cite this cell line use: HEK293-MRP7 (RRID:CVCL_B3Q1)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:52; ABCC10.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=26579384; DOI=10.1016/j.apsb.2014.02.003; PMCID=PMC4629066
Nagaraju Anreddy, Atish Patel, Kamlesh Sodani, Rishil J. Kathawala, Eugenie P. Chen, John N.D. Wurpel, Zhe-Sheng Chen;
PD173074, a selective FGFR inhibitor, reverses MRP7 (ABCC10)-mediated MDR.
Acta Pharm. Sin. B. 4:202-207(2014)

PubMed=34631561; DOI=10.3389/fonc.2021.731260; PMCID=PMC8498192
Jing-Quan Wang, Zhuo-Xun Wu, Yuqi Yang, Jin-Sui Li, Dong-Hua Yang, Ying-Fang Fan, Zhe-Sheng Chen;
Establishment and characterization of a novel multidrug resistant human ovarian cancer cell line with heterogenous MRP7 overexpression.
Front. Oncol. 11:731260.1-731260.10(2021)

Cross-references
Encyclopedic resources Wikidata; Q110432862
Entry history
Entry creation16-Dec-2021
Last entry update14-Aug-2025
Version number7