Cellosaurus cell line UOK353 (CVCL

Cross-references
Cell line name	UOK353
Accession	CVCL_B3PQ
Resource Identification Initiative	To cite this cell line use: UOK353 (RRID:CVCL_B3PQ)
Comments	Population: African American. Doubling time: ~72 hours (PubMed=32259323). Karyotypic information: 43,XX,-4,-9,-15,t(19;22)(p13.1;q11.2) (PubMed=32259323). Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg181His (c.542G>A); ClinVar=VCV000142320; Zygosity=Heterozygous (PubMed=32259323).
Disease	Kidney medullary carcinoma (NCIt: C7572) Renal medullary carcinoma (ORDO: Orphanet_319319)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	42Y
Category	Cancer cell line
Publications	PubMed=32259323; DOI=10.1002/gcc.22847; PMCID=PMC7383978 Darmood Wei, You-Feng Yang, Christopher J. Ricketts, Cathy D. Vocke, Mark W. Ball, Carole Sourbier, Darawalee Wangsa Zong, Danny Wangsa, Rajarshi Guha, Xiao-Hu Zhang, Kelli M. Wilson ...Show all 17 authors... , Lu Chen, Paul S. Meltzer, Thomas Ried, Craig J. Thomas, Maria J. Merino, William Marston Linehan; Show fewer authors Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments. Genes Chromosomes Cancer 59:472-483(2020)
Cell line databases/resources	cancercelllines; CVCL_B3PQ
Encyclopedic resources	Wikidata; Q110433949
Entry history
Entry creation	16-Dec-2021
Last entry update	19-Dec-2024
Version number	6