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Cellosaurus CHIpMSC3 (CVCL_B3MR)

[Text version]
Cell line name CHIpMSC3
Synonyms D-CHI
Accession CVCL_B3MR
Resource Identification Initiative To cite this cell line use: CHIpMSC3 (RRID:CVCL_B3MR)
Comments Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Cell type: Mesenchymal stem cell; CL=CL_0000134.
Sequence variations
  • Mutation; HGNC; HGNC:59; ABCC8; Simple; p.Arg1493Gln (c.4478G>A) (R1494Q); ClinVar=VCV000370910; Zygosity=Homozygous (PubMed=31525223).
Disease Persistent hyperinsulinemic hypoglycemia of infancy (NCIt: C122923)
Autosomal dominant hyperinsulinism due to SUR1 deficiency (ORDO: Orphanet_276575)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 11W
Category Somatic stem cell
STR profile Source(s): CelloPub=CLPUB00652

Markers:
AmelogeninX,Y
CSF1PO12
D3S135815
D5S81812,13
D7S8208,10
D8S117912,15
D13S3178,11
D16S53911,13
D18S5115,16
D21S1131.2,32.2
FGA23,25
Penta D8,10
Penta E11,14
TH017,9.3
TPOX8,11
vWA16,18

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Publications

CLPUB00652
Kellaway S.G.
Stem cells from patients with congenital hyperinsulinism.
Thesis PhD (2016); University of Manchester; Manchester; United Kingdom

PubMed=31525223; DOI=10.1371/journal.pone.0222350; PMCID=PMC6746350
Kellaway S.G., Mosinska K., Mohamed Z., Ryan A., Richardson S.M., Newbould M., Banerjee I., Dunne M.J., Cosgrove K.E.
Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism.
PLoS ONE 14:e0222350.1-e0222350.16(2019)

Cross-references
Encyclopedic resources Wikidata; Q110432708
Entry history
Entry creation16-Dec-2021
Last entry update19-Dec-2024
Version number5