Cellosaurus cell line CHIpMSC1 (CVCL

Cellosaurus CHIpMSC1 (CVCL_B3MQ)

[Text version]

Cell line name

CHIpMSC1

Synonyms

F-CHI

Accession

CVCL_B3MQ

Resource Identification Initiative

To cite this cell line use: CHIpMSC1 (RRID:CVCL_B3MQ)

Comments

Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Cell type: Mesenchymal stem cell; CL=CL_0000134.

Sequence variations

Mutation; HGNC; HGNC:59; ABCC8; Simple; p.Gly316Arg (c.946G>A); ClinVar=VCV001687413; Zygosity=Heterozygous (PubMed=31525223).

Disease

Persistent hyperinsulinemic hypoglycemia of infancy (NCIt: C122923)
Autosomal dominant hyperinsulinism due to SUR1 deficiency (ORDO: Orphanet_276575)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

Category

Somatic stem cell

STR profile

Source(s): CelloPub=CLPUB00652

Markers:

Amelogenin	X,Y
CSF1PO	11,13
D3S1358	14,18
D5S818	11,12
D7S820	11
D8S1179	13,15
D13S317	8,12
D16S539	12
D18S51	12
D21S11	27,29
FGA	19,21
Penta D	9,12
Penta E	7,12
TH01	7,9.3
TPOX	10,11
vWA	14

Publications

CLPUB00652
Sophie Grace Kellaway;
Stem cells from patients with congenital hyperinsulinism.
Thesis PhD (2016); University of Manchester; Manchester; United Kingdom

PubMed=31525223; DOI=10.1371/journal.pone.0222350; PMCID=PMC6746350
Sophie Grace Kellaway, Karolina Mosinska, Zainaba Mohamed, Alexander Ryan, Stephen M. Richardson, Melanie Newbould, Indraneel Banerjee, Mark J. Dunne, Karen E. Cosgrove;
Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism.
PLoS ONE 14:e0222350.1-e0222350.16(2019)

Cross-references

Encyclopedic resources

Wikidata; Q110432706

Entry history

Entry creation

16-Dec-2021

Last entry update

19-Dec-2024

Version number