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Cellosaurus D21-iPSC#1 (CVCL_B3LX)

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Cell line name D21-iPSC#1
Synonyms AF4 iPS #12-2-C
Accession CVCL_B3LX
Resource Identification Initiative To cite this cell line use: D21-iPSC#1 (RRID:CVCL_B3LX)
Comments Characteristics: While originating from a Down syndrome patient, this cell line has lost the extra copy of chromosome 21.
Karyotypic information: 46,XX [17/20]; 45,X [1/20]; 45,XX,-12 [1/20]; 90,XXXX,-14,-17 [1/20] (JCRB=JCRB1836).
Derived from site: In situ; Amniotic fluid; UBERON=UBERON_0000173.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B3M2 (T21-iPSC#12)
Sex of cell Female
Age at sampling Fetus
Category Induced pluripotent stem cell
STR profile Source(s): JCRB=JCRB1836; PubMed=30760866

Markers:
AmelogeninX
CSF1PO10
D3S135815,16
D5S81812
D7S82010,12
D8S117912,13
D13S31711,12
D16S5399,11
D18S5113,15
D21S1131,32
FGA22
Penta D9,11
Penta E12,19
TH016,7
TPOX10,12
vWA14,19

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Publications

PubMed=30760866; DOI=10.1038/s41374-019-0230-0; PMCID=PMC6760570
Momoko Inoue, Kazuhiro Kajiwara, Ayumi Yamaguchi, Tohru Kiyono, Osamu Samura, Hidenori Akutsu, Haruhiko Sago, Aikou Okamoto, Akihiro Umezawa;
Autonomous trisomic rescue of Down syndrome cells.
Lab. Invest. 99:885-897(2019)

Cross-references
Cell line collections (Providers) JCRB; JCRB1836
Encyclopedic resources Wikidata; Q110432765
Entry history
Entry creation16-Dec-2021
Last entry update02-May-2024
Version number6