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Cellosaurus TL-1 (CVCL_B371)

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Cell line name TL-1
Synonyms TL1
Accession CVCL_B371
Resource Identification Initiative To cite this cell line use: TL-1 (RRID:CVCL_B371)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Virology: EBV-negative.
Doubling time: ~36 hours (PubMed=2486610; PubMed=6268866).
Derived from site: In situ; Ileocecal lymph node; UBERON=UBERON_8480054.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:5362; ID3; Simple; p.Glu53Ter (c.157G>T); Zygosity=Heterozygous (DepMap=ACH-002055).
  • Mutation; HGNC; HGNC:7672; NCOR1; Simple; p.Ile1927fs (c.5779_5780delAT); Zygosity=Heterozygous (DepMap=ACH-002055).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr236Ser (c.707A>C); ClinVar=VCV000182966; Zygosity=Homozygous (DepMap=ACH-002055).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 10Y
Category Cancer cell line
STR profile Source(s): RCB=RCB1871; TKG=TKG 0607

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81810,12
D7S82010,12
D13S3178,11
D16S53912
TH016,7
TPOX9,11
vWA14,19

Run an STR similarity search on this cell line
Publications

PubMed=6268866
Yutaka Hayashi, Yoshikazu Matsumura, Tetsuro Nishihira, Itaru Watanabe, Ryoji Ohi, Morio Kasai, Katsuo Kumagai, Nanao Kamada;
Burkitt's lymphoma cell line bearing surface IgA and negative for nuclear antigen of Epstein-Barr virus (EBNA).
Jpn. J. Exp. Med. 50:423-434(1980)

PubMed=2486610
Seiichi Yaoita, Ryoji Ohoi, Yutaka Hayashi, Takao Watanabe;
Establishment and characterization of TL-1 cell line from a ileo-cecal Burkitt's lymphoma.
Hum. Cell 2:197-197(1989)

Cross-references
Cell line collections (Providers) RCB; RCB1871
TKG; TKG 0607
Cell line databases/resources CLO; CLO_0050020
DepMap; ACH-002055
Biological sample resources BioSample; SAMN03472078
Encyclopedic resources Wikidata; Q54972597
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number18