Cellosaurus cell line DF508 4 (CVCL

Cross-references
Cell line name	DF508 4
Accession	CVCL_B337
Resource Identification Initiative	To cite this cell line use: DF508 4 (RRID:CVCL_B337)
Comments	From: Boston University School of Medicine; Boston; USA. Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=20715179).
Disease	Cystic fibrosis (NCIt: C2975) Cystic fibrosis (ORDO: Orphanet_586)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_L744 (GM01012)
Sex of cell	Male
Age at sampling	8Y
Category	Induced pluripotent stem cell
Publications	PubMed=20715179; DOI=10.1002/stem.495; PMCID=PMC3422663 Aba Somers, Jyh-Chang Jean, Cesar A. Sommer, Amel Omari, Christopher C. Ford, Jason A. Mills, Lei Ying, Andreia Gianotti-Sommer, Jenny M. Jean, Brenden W. Smith, Robert Lafyatis ...Show all 18 authors... , Marie-France Demierre, Daniel J. Weiss, Deborah L. French, Paul Gadue, George J. Murphy, Gustavo Mostoslavsky, Darrell N. Kotton; Show fewer authors Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette. Stem Cells 28:1728-1740(2010)
Encyclopedic resources	Wikidata; Q54831026
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	21