Cellosaurus cell line NAN-4 (CVCL

Cellosaurus NAN-4 (CVCL_B319)

Cross-references
Cell line name	NAN-4
Synonyms	NAN4
Accession	CVCL_B319
Resource Identification Initiative	To cite this cell line use: NAN-4 (RRID:CVCL_B319)
Comments	Characteristics: Produces IgA kappa. Characteristics: IL6 dependent. Miscellaneous: Cell line has been lost (personal communication of Pellat-Deceunynck, Catherine). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: Plasma cell; CL=CL_0000786.
Disease	Plasma cell myeloma (NCIt: C3242) Multiple myeloma (ORDO: Orphanet_29073)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=16638930; DOI=10.1182/blood-2005-12-007971 Emmanuelle Menoret, Patricia Gomez-Bougie, Alexandrine Geffroy-Luseau, Sylvanne Daniels, Philippe Moreau, Steven Le Gouill, Jean-Luc Harousseau, Francois-Regis Bataille, Martine Amiot, Catherine Pellat-Deceunynck; Mcl-1L cleavage is involved in TRAIL-R1- and TRAIL-R2-mediated apoptosis induced by HGS-ETR1 and HGS-ETR2 human mAbs in myeloma cells. Blood 108:1346-1352(2006) PubMed=16956823 Francois-Regis Bataille, Gaatan Jego, Nelly Robillard, Sophie Barille-Nion, Jean-Luc Harousseau, Philippe Moreau, Martine Amiot, Catherine Pellat-Deceunynck; The phenotype of normal, reactive and malignant plasma cells Identification of 'many and multiple myelomas' and of new targets for myeloma therapy. Haematologica 91:1234-1240(2006)
Encyclopedic resources	Wikidata; Q54907477
Entry history
Entry creation	06-Jun-2012
Last entry update	14-Aug-2025
Version number	16