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Cellosaurus Abcam A-549 SFRP1 KO (CVCL_B2Q1)

[Text version]
Cell line name Abcam A-549 SFRP1 KO
Synonyms Human SFRP1 knockout A549
Accession CVCL_B2Q1
Resource Identification Initiative To cite this cell line use: Abcam A-549 SFRP1 KO (RRID:CVCL_B2Q1)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10776; SFRP1.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=39319244; DOI=10.12688/f1000research.130991.2; PMCID=PMC11420615
Ayoubi R., Southern K., Laflamme C.
NeuroSGC/YCharOS Collaborative Group
A guide to selecting high-performing antibodies for secreted frizzled-related protein 1 (sFRP-1) for use in western blot and immunoprecipitation.
F1000Research 12:291.1-291.12(2023)

Cross-references
Cell line collections (Providers) Abcam; ab277906
Cell line databases/resources cancercelllines; CVCL_B2Q1
Encyclopedic resources Wikidata; Q110430249
Entry history
Entry creation16-Dec-2021
Last entry update10-Apr-2025
Version number7