Cellosaurus cell line Sup-M2-TS (CVCL

Cellosaurus Sup-M2-TS (CVCL_B228)

Cross-references
Cell line name	Sup-M2-TS
Synonyms	Sup-M2TS; TS
Accession	CVCL_B228
Resource Identification Initiative	To cite this cell line use: Sup-M2-TS (RRID:CVCL_B228)
Comments	Population: Caucasian. Derived from site: In situ; Cerebrospinal fluid; UBERON=UBERON_0001359.
Sequence variations	Gene fusion; HGNC; HGNC:427; ALK + HGNC; HGNC:7910; NPM1; Name(s)=NPM1-ALK (PubMed=26657151).
Disease	Anaplastic large cell lymphoma, ALK-positive (NCIt: C37193) ALK-positive anaplastic large cell lymphoma (ORDO: Orphanet_300895)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_2209 (SUP-M2)
Sex of cell	Female
Age at sampling	5Y
Category	Cancer cell line
Publications	PubMed=26657151; DOI=10.1038/onc.2015.456; PMCID=PMC4907875 Monica Ceccon, Maria Elena Boggio Merlo, Luca Mologni, Teresa Poggio, Lydia M. Varesio, Matteo Menotti, Silvia Bombelli, Roberta Rigolio, Andrea D. Manazza, Filomena Di Giacomo, Chiara Ambrogio ...Show all 19 authors... , Giovanni Giudici, Cesare Casati, Cristina Mastini, Mara Compagno, Suzanne D. Turner, Carlo Gambacorti-Passerini, Roberto Chiarle, Claudia Voena; Show fewer authors Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency. Oncogene 35:3854-3865(2016)
Cell line databases/resources	cancercelllines; CVCL_B228
Anatomy/cell type resources	BTO; BTO_0004867
Encyclopedic resources	Wikidata; Q54970879
Gene expression databases	GEO; GSM1217149
Polymorphism and mutation databases	Progenetix; CVCL_B228
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	18