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Cellosaurus HUES 48 (CVCL_B181)

[Text version]
Cell line name HUES 48
Synonyms HUES48; HuES48
Accession CVCL_B181
Resource Identification Initiative To cite this cell line use: HUES 48 (RRID:CVCL_B181)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0053.
Omics: Genomics; ChIP-seq; H3K27ac.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K36me3.
Omics: Genomics; ChIP-seq; H3K4me1.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Genomics; ChIP-seq; H3K9ac.
Omics: Genomics; ChIP-seq; H3K9me3.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798

Markers:
AmelogeninX
CSF1PO11,12
D2S133820,21
D3S135815,16
D5S81812,13
D7S8209
D8S117910,13
D13S31712,13
D16S53911,12
D18S5112,13
D19S43314,15
D21S1130.2,31.2
FGA21,24
TH019.3
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001; PMCID=PMC3335201
Chen A.E., Egli D.M., Niakan K.K., Deng J., Akutsu H., Yamaki M., Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=21295703; DOI=10.1016/j.cell.2010.12.032; PMCID=PMC3063454
Bock C., Kiskinis E., Verstappen G., Gu H.-C., Boulting G.L., Smith Z.D., Ziller M.J., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K.C., Meissner A.
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell 144:439-452(2011)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-10-0053
SKIP; SKIP001529
Biological sample resources BioSample; SAMN00849560
BioSample; SAMN03732527
BioSample; SAMN04096428
ENCODE; ENCBS099BXQ
ENCODE; ENCBS203SNR
ENCODE; ENCBS395IFY
ENCODE; ENCBS585ALE
Encyclopedic resources Wikidata; Q54896785
Experimental variables resources EFO; EFO_0007083
Gene expression databases GEO; GSM621598
GEO; GSM637767
GEO; GSM669936
GEO; GSM669942
GEO; GSM669954
GEO; GSM670013
GEO; GSM670039
GEO; GSM772755
GEO; GSM772766
GEO; GSM772780
GEO; GSM772793
GEO; GSM772794
GEO; GSM772796
GEO; GSM772797
GEO; GSM772798
GEO; GSM772799
GEO; GSM909322
GEO; GSM997250
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number24