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Cellosaurus HUES 48 (CVCL_B181)

[Text version]
Cell line name HUES 48
Synonyms HUES48; HuES48
Accession CVCL_B181
Resource Identification Initiative To cite this cell line use: HUES 48 (RRID:CVCL_B181)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0053.
Omics: Genomics; ChIP-seq; H3K27ac.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K36me3.
Omics: Genomics; ChIP-seq; H3K4me1.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Genomics; ChIP-seq; H3K9ac.
Omics: Genomics; ChIP-seq; H3K9me3.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798

Markers:
AmelogeninX
CSF1PO11,12
D2S133820,21
D3S135815,16
D5S81812,13
D7S8209
D8S117910,13
D13S31712,13
D16S53911,12
D18S5112,13
D19S43314,15
D21S1130.2,31.2
FGA21,24
TH019.3
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001; PMCID=PMC3335201
Alice E. Chen, Dietrich Meinrad Egli, Kathy K. Niakan, Jie Deng, Hidenori Akutsu, Mariko Yamaki, Chad A. Cowan, Claire Fitz-Gerald, Kun Zhang, Douglas A. Melton, Kevin Carl Eggan;
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=21295703; DOI=10.1016/j.cell.2010.12.032; PMCID=PMC3063454
Christoph Bock, Evangelos Kiskinis, Griet Verstappen, Hong-Cang Gu, Gabriella L. Boulting, Zachary D. Smith, Michael Johannes Ziller, Gist Fralley Croft, Mackenzie Weygandt Amoroso, Derek H. Oakley, Andreas Gnirke ...Show all 13 authors... , Kevin Carl Eggan, Alexander Meissner; Show fewer authors
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell 144:439-452(2011)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-10-0053
SKIP; SKIP001529
Biological sample resources BioSample; SAMN00849560
BioSample; SAMN03732527
BioSample; SAMN04096428
ENCODE; ENCBS099BXQ
ENCODE; ENCBS203SNR
ENCODE; ENCBS395IFY
ENCODE; ENCBS585ALE
Encyclopedic resources Wikidata; Q54896785
Experimental variables resources EFO; EFO_0007083
Gene expression databases GEO; GSM621598
GEO; GSM637767
GEO; GSM669936
GEO; GSM669942
GEO; GSM669954
GEO; GSM670013
GEO; GSM670039
GEO; GSM772755
GEO; GSM772766
GEO; GSM772780
GEO; GSM772793
GEO; GSM772794
GEO; GSM772796
GEO; GSM772797
GEO; GSM772798
GEO; GSM772799
GEO; GSM909322
GEO; GSM997250
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number24