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Cellosaurus HUES 42 (CVCL_B175)

[Text version]
Cell line name HUES 42
Synonyms HUES42; HuES42
Accession CVCL_B175
Resource Identification Initiative To cite this cell line use: HUES 42 (RRID:CVCL_B175)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-12-0157.
Omics: Genomics; Whole exome sequencing.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798

Markers:
AmelogeninX,Y
CSF1PO11
D2S133817,24
D3S135818
D5S81811,12
D7S8209,10
D8S117910,15
D13S31711
D16S53911,12
D18S5117,20
D19S43314,15
D21S1128,31.2
FGA20,24
TH016,9.3
TPOX8
vWA18,19

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Publications

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001; PMCID=PMC3335201
Chen A.E., Egli D.M., Niakan K.K., Deng J., Akutsu H., Yamaki M., Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-12-0157
SKIP; SKIP001524
Encyclopedic resources Wikidata; Q54896777
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number19