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Cellosaurus HUES 42 (CVCL_B175)

[Text version]
Cell line name HUES 42
Synonyms HUES42; HuES42
Accession CVCL_B175
Resource Identification Initiative To cite this cell line use: HUES 42 (RRID:CVCL_B175)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-12-0157.
Omics: Genomics; Whole exome sequencing.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798

Markers:
AmelogeninX,Y
CSF1PO11
D2S133817,24
D3S135818
D5S81811,12
D7S8209,10
D8S117910,15
D13S31711
D16S53911,12
D18S5117,20
D19S43314,15
D21S1128,31.2
FGA20,24
TH016,9.3
TPOX8
vWA18,19

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Publications

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001; PMCID=PMC3335201
Alice E. Chen, Dietrich Meinrad Egli, Kathy K. Niakan, Jie Deng, Hidenori Akutsu, Mariko Yamaki, Chad A. Cowan, Claire Fitz-Gerald, Kun Zhang, Douglas A. Melton, Kevin Carl Eggan;
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-12-0157
SKIP; SKIP001524
Encyclopedic resources Wikidata; Q54896777
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number19