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Cellosaurus UOK130 (CVCL_B112)

[Text version]
Cell line name UOK130
Synonyms UOK-130; UOK 130
Accession CVCL_B112
Resource Identification Initiative To cite this cell line use: UOK130 (RRID:CVCL_B112)
Comments Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:12687; VHL; Simple; p.Leu153Pro (c.458T>C); Zygosity=Unspecified (PubMed=7915601).
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_4Z16 (UOKCR)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=1345811
Patrick Anglard, Emile Elie Trahan Jr., Sue Liu, Farida Latif, Maria J. Merino, Michael I. Lerman, Berton Zbar, William Marston Linehan;
Molecular and cellular characterization of human renal cell carcinoma cell lines.
Cancer Res. 52:348-356(1992)

PubMed=8319216
Robert E. Reiter, Patrick Anglard, Sue Liu, James R. Gnarra, William Marston Linehan;
Chromosome 17p deletions and p53 mutations in renal cell carcinoma.
Cancer Res. 53:3092-3097(1993)

PubMed=7915601; DOI=10.1038/ng0594-85
James R. Gnarra, Kalman Tory, Yong-Kai Weng, Laura S. Schmidt, Ming Hui Wei, H. Li, Farida Latif, S. Liu, Fan Chen, Fuh-Mei Duh, Irina A. Lubensky ...Show all 24 authors... , Dah-Shuhn R. Duan, Charles Florence, Rudy Pozzatti, McClellan Milton Walther, Neil Harrison Bander, Herbert Barton Grossman, Hiltrud Brauch, Sigmund Pomer, James D. Brooks, William B. Isaacs, Michael I. Lerman, Berton Zbar, William Marston Linehan; Show fewer authors
Mutations of the VHL tumour suppressor gene in renal carcinoma.
Nat. Genet. 7:85-90(1994)

PubMed=12759923; DOI=10.1002/gcc.10209
Christian P. Pavlovich, Hesed Maria Padilla-Nash, Danny Wangsa, Michael L. Nickerson, Vera Matrosova, William Marston Linehan, Thomas Ried, John L. Phillips;
Patterns of aneuploidy in stage IV clear cell renal cell carcinoma revealed by comparative genomic hybridization and spectral karyotyping.
Genes Chromosomes Cancer 37:252-260(2003)

PubMed=17509556; DOI=10.1016/j.ejphar.2007.04.021
Wei Wang, Guang-Xian Liu, Jiang Zheng;
Human renal UOK130 tumor cells: a drug resistant cell line with highly selective over-expression of glutathione S-transferase-pi isozyme.
Eur. J. Pharmacol. 568:61-67(2007)

Cross-references
Cell line databases/resources SKY/M-FISH/CGH; 1527
Encyclopedic resources Wikidata; Q54991357
Polymorphism and mutation databases Cosmic; 972897
Cosmic; 981000
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number14