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Cellosaurus 293T/ACE2 [Japan 2021] (CVCL_B0XR)

[Text version]
Cell line name 293T/ACE2 [Japan 2021]
Accession CVCL_B0XR
Resource Identification Initiative To cite this cell line use: 293T/ACE2 [Japan 2021] (RRID:CVCL_B0XR)
Comments Group: SARS-CoV-2 research cell line.
Virology: Highly susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33686154).
Transfected with: HGNC; 13557; ACE2.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=tsA].
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=33686154; DOI=10.1038/s41598-021-84882-7
Uemura K., Sasaki M., Sanaki T., Toba S., Takahashi Y., Orba Y., Hall W.W., Maenaka K., Sawa H., Sato A.
MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2.
Sci. Rep. 11:5376-5376(2021)

Cross-references
Encyclopedic resources Wikidata; Q108819503
Entry history
Entry creation23-Sep-2021
Last entry update05-Oct-2023
Version number6