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Cellosaurus HEK293-FT APEX1 KO clone 1C4 (CVCL_B0WA)

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Cell line name HEK293-FT APEX1 KO clone 1C4
Synonyms 1C4
Accession CVCL_B0WA
Resource Identification Initiative To cite this cell line use: HEK293-FT APEX1 KO clone 1C4 (RRID:CVCL_B0WA)
Comments Doubling time: 20.4 hours (PubMed=34529719).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:587; APEX1.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6911 (HEK293-FT)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=34529719; DOI=10.1371/journal.pone.0257473; PMCID=PMC8445474
Daria V. Kim, Liliya M. Kulishova, Natalia A. Torgasheva, Vasily S. Melentyev, Grigory L. Dianov, Sergey P. Medvedev, Suren Minasovich Zakian, Dmitry O. Zharkov;
Mild phenotype of knockouts of the major apurinic/apyrimidinic endonuclease APEX1 in a non-cancer human cell line.
PLoS ONE 16:e0257473.1-e0257473.19(2021)

Cross-references
Encyclopedic resources Wikidata; Q108820444
Entry history
Entry creation23-Sep-2021
Last entry update14-Aug-2025
Version number6