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Cellosaurus 491 (CVCL_B0V4)

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Cell line name 491
Accession CVCL_B0V4
Resource Identification Initiative To cite this cell line use: 491 (RRID:CVCL_B0V4)
Comments Misspelling: FK99-491; IARC_TP53=11554; Note=Not really a misspelling but an assignment of a name based on first author of publication.
Derived from site: In situ; Synovium; UBERON=UBERON_0007616.
Cell type: Fibroblast; CL=CL_0000057.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp207Asp (c.621T>C); Zygosity=Unspecified (PubMed=10446856).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Phe212Tyr (c.635T>A); Zygosity=Unspecified (PubMed=10446856).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg290Cys (c.868C>T); ClinVar=VCV000216472; Zygosity=Unspecified (PubMed=10446856).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Finite cell line
Publications

PubMed=10446856; DOI=10.1002/1529-0131(199908)42:8<1594::AID-ANR5>3.0.CO;2-#
Frank Kullmann, Martin Judex, Ingrid Neudecker, Sandra Lechner, Hans-Peter Justen, Douglas Ronald Green, Dieter Wessinghage, Gary S. Firestein, Steffen Gay, Jurgen Scholmerich, Ulf Muller-Ladner;
Analysis of the p53 tumor suppressor gene in rheumatoid arthritis synovial fibroblasts.
Arthritis Rheum. 42:1594-1600(1999)

Cross-references
Encyclopedic resources Wikidata; Q108819635
Polymorphism and mutation databases IARC_TP53; 11554
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number5