Cellosaurus cell line 2C7 [Mouse hybridoma against N.gonorrhoease LOS] (CVCL

Cellosaurus 2C7 [Mouse hybridoma against N.gonorrhoease LOS] (CVCL_B0E6)

Cross-references
Cell line name	2C7 [Mouse hybridoma against N.gonorrhoease LOS]
Accession	CVCL_B0E6
Resource Identification Initiative	To cite this cell line use: 2C7 [Mouse hybridoma against N.gonorrhoease LOS] (RRID:CVCL_B0E6)
Comments	Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-11859. Monoclonal antibody isotype: IgG3, lambda. Monoclonal antibody target: Neisseria gonorrhoeae lipo-oligosaccharide (LOS) (Note=Binds to the inner 15253 LOS structure found within WG LOS).
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy	Parent: CVCL_2199 (Sp2/0-Ag14)
Category	Hybridoma
Publications	PubMed=2428752; DOI=10.1128/IAI.54.1.63-69.1986; PMCID=PMC260117 Robert Mandrell, Herman Schneider, Michael A. Apicella, Wendell David Zollinger, Peter A. Rice, John McLeod Griffiss; Antigenic and physical diversity of Neisseria gonorrhoeae lipooligosaccharides. Infect. Immun. 54:63-69(1986) PubMed=10593954; DOI=10.1074/jbc.274.51.36550 Ryohei Yamasaki, Hiroyuki Koshino, Sadamu Kurono, Yumiko Nishinaka, Daniel P. McQuillen, Akiko Kume, Sunita Gulati, Peter A. Rice; Structural and immunochemical characterization of a Neisseria gonorrhoeae epitope defined by a monoclonal antibody 2C7; the antibody recognizes a conserved epitope on specific lipo-oligosaccharides in spite of the presence of human carbohydrate epitopes. J. Biol. Chem. 274:36550-36558(1999) Patent=US6099839 Peter A. Rice, Sunita Gulati, Daniel P. McQuillen; Gonococcal anti-idiotypic antibodies and methods compositions using them. Patent number US6099839, 08-Aug-2000 PubMed=11878767; DOI=10.3109/08830180109043036 Sunita Gulati, Jutamas Ngampasutadol, Ryohei Yamasaki, Daniel P. McQuillen, Peter A. Rice; Strategies for mimicking Neisserial saccharide epitopes as vaccines. Int. Rev. Immunol. 20:229-250(2001)
Encyclopedic resources	Wikidata; Q108819515
Entry history
Entry creation	23-Sep-2021
Last entry update	21-Mar-2023
Version number	4