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Cellosaurus RAO-2 (CVCL_B0CK)

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Cell line name RAO-2
Accession CVCL_B0CK
Resource Identification Initiative To cite this cell line use: RAO-2 (RRID:CVCL_B0CK)
Comments Characteristics: Does not show anchorage-independent growth in soft agar and is not tumorigenic in nude mice (PubMed=16395697).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gln61Leu).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B0CJ (RAO-1)
Sex of cell Female
Age at sampling Age unspecified
Category Telomerase immortalized cell line
Publications

PubMed=16395697; DOI=10.1002/ijc.21739
Ji-Ming Cheng, Ming Ding, Ahmed Aribi, Prabodh Shah, Krishna Rao;
Loss of RAB25 expression in breast cancer.
Int. J. Cancer 118:2957-2964(2006)

PubMed=16729884; DOI=10.1186/1475-2867-6-15; PMCID=PMC1524989
Krishna Rao, Ozge Alper, Kent E. Opheim, George Bonnet, Kristine Wolfe, Eileen Mary Bryant, Siobhan Margaret O'Hara Larivee, Peggy L. Porter, James Kinloch McDougall;
Cytogenetic characterization and H-ras associated transformation of immortalized human mammary epithelial cells.
Cancer Cell Int. 6:15.1-15.11(2006)

Cross-references
Encyclopedic resources Wikidata; Q108821206
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number6