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Cellosaurus MEL114433 (CVCL_B0CE)

[Text version]
Cell line name MEL114433
Synonyms Mel114433; Melanoma model 1; M1
Accession CVCL_B0CE
Resource Identification Initiative To cite this cell line use: MEL114433 (RRID:CVCL_B0CE)
Comments Doubling time: ~24 hours (ATCC=CRL-3473).
Transformant: NCIt; C17231; Ultraviolet radiation.
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 BrafCA/+, Ptenflox/+, Cdkn2aflox/+, Tyr-CreERT2-tg.
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=32284588; DOI=10.1038/s41591-020-0818-3; PMCID=PMC8482620
Perez-Guijarro E., Yang H.H., Araya R.E., El Meskini R., Michael H.T., Vodnala S.K., Marie K.L., Smith C., Chin S., Lam K.C., Thorkelsson A., Iacovelli A.J., Kulaga A., Fon A.-Y., Michalowski A.M., Hugo W., Lo R.S., Restifo N.P., Sharan S.K., Van Dyke T., Goldszmid R.S., Ohler Z.W., Lee M.P., Day C.-P., Merlino G.T.
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Nat. Med. 26:781-791(2020)

Cross-references
Cell line collections (Providers) ATCC; CRL-3473
Encyclopedic resources Wikidata; Q108820900
Gene expression databases GEO; GSM4301282
Entry history
Entry creation23-Sep-2021
Last entry update10-Apr-2025
Version number6