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Cellosaurus HNPSV-1 (CVCL_B0BI)

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Cell line name HNPSV-1
Synonyms Human Nucleus Pulposus SV40-transformed-1
Accession CVCL_B0BI
Resource Identification Initiative To cite this cell line use: HNPSV-1 (RRID:CVCL_B0BI)
Comments Population: Japanese.
Senescence: Transformed but with a finite life span. Senesces at 60-100 PDL (PubMed=15247572).
Transformant: Ad12-SV40 hybrid virus.
Derived from site: In situ; Intervertebral disc, nucleus pulposus; UBERON=UBERON_0002242.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 19Y
Category Transformed cell line
Publications

PubMed=15247572; DOI=10.1097/01.brs.0000131419.25265.23
Daisuke Sakai, Joji Mochida, Yukihiro Yamamoto, Eiren Toh, Toru Iwashina, Takeshi Miyazaki, Sadaki Inokuchi, Kiyoshi Ando, Tomomitsu Hotta;
Immortalization of human nucleus pulposus cells by a recombinant SV40 adenovirus vector: establishment of a novel cell line for the study of human nucleus pulposus cells.
Spine 29:1515-1523(2004)

PubMed=16102816; DOI=10.1016/j.biomaterials.2005.06.040
Daisuke Sakai, Joji Mochida, Toru Iwashina, Takuya Watanabe, Kaori Suyama, Kiyoshi Ando, Tomomitsu Hotta;
Atelocollagen for culture of human nucleus pulposus cells forming nucleus pulposus-like tissue in vitro: influence on the proliferation and proteoglycan production of HNPSV-1 cells.
Biomaterials 27:346-353(2006)

PubMed=19598131; DOI=10.22203/ecm.v017a02
Yuka Kobayashi, Daisuke Sakai, Toru Iwashina, Sadahiro Iwabuchi, Joji Mochida;
Low-intensity pulsed ultrasound stimulates cell proliferation, proteoglycan synthesis and expression of growth factor-related genes in human nucleus pulposus cell line.
Eur. Cell. Mater. 17:15-22(2009)

Cross-references
Encyclopedic resources Wikidata; Q108820490
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number5