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Cellosaurus CX16-RV2 Ecto (CVCL_B0A8)

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Cell line name CX16-RV2 Ecto
Accession CVCL_B0A8
Resource Identification Initiative To cite this cell line use: CX16-RV2 Ecto (RRID:CVCL_B0A8)
Comments Doubling time: ~30-40 hours (ATCC=CRL-3458).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Uterus, cervix, ectocervical epithelium; UBERON=UBERON_0012251.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B0A9 ! CX16-RV2 Endo
CVCL_B0AA ! CX16-RV2 TZ
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): ATCC=CRL-3458; PubMed=29944714

Markers:
AmelogeninX
CSF1PO11
D5S81811,13
D7S8209,10
D13S31712
D16S5399,11
TH017
TPOX9,11
vWA15

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Publications

PubMed=29944714; DOI=10.1371/journal.pone.0199761; PMCID=PMC6019754
Han Deng, Eric Hillpot, Philomina Yeboah, Sumona Mondal, Craig D. Woodworth;
Susceptibility of epithelial cells cultured from different regions of human cervix to HPV16-induced immortalization.
PLoS ONE 13:e0199761.1-e0199761.16(2018)

PubMed=30337615; DOI=10.1038/s41598-018-33865-2; PMCID=PMC6194146
Han Deng, Eric Hillpot, Sumona Mondal, Kamal K. Khurana, Craig D. Woodworth;
HPV16-immortalized cells from human transformation zone and endocervix are more dysplastic than ectocervical cells in organotypic culture.
Sci. Rep. 8:15402.1-15402.13(2018)

Cross-references
Cell line collections (Providers) ATCC; CRL-3458
Encyclopedic resources Wikidata; Q108820108
Entry history
Entry creation23-Sep-2021
Last entry update14-Aug-2025
Version number9