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Cellosaurus SN-1 (CVCL_B075)

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Cell line name SN-1
Accession CVCL_B075
Resource Identification Initiative To cite this cell line use: SN-1 (RRID:CVCL_B075)
Comments Population: Japanese.
Doubling time: 28 hours (PubMed=10706136).
Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: T-cell; CL=CL_0000084.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 2Y
Category Cancer cell line
Publications

PubMed=10233379; DOI=10.1111/j.1365-2141.1999.01284.x
Feng Xu, Tomohiko Taki, Hong-Wei Yang, Ryoji Hanada, Teruaki Hongo, Hiroaki Ohnishi, Miyuki Kobayashi, Fumio Bessho, Masayoshi Yanagisawa, Yasuhide Hayashi;
Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children.
Br. J. Haematol. 105:155-162(1999)

PubMed=10706136
Yasuhide Hayashi, Yoshio Honma, Nozomi Niitsu, Tomohiko Taki, Fumio Bessho, Masahiro Sako, Taijiro Mori, Masayoshi Yanagisawa, Kohichiro Tsuji, Tatsutoshi Nakahata;
SN-1, a novel leukemic cell line with t(11;16)(q23;p13): myeloid characteristics and resistance to retinoids and vitamin D3.
Cancer Res. 60:1139-1145(2000)

PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4
Kaoru Inoue, Takashi Kohno, Satoshi Takakura, Yasuhide Hayashi, Hideaki Mizoguchi, Jun Yokota;
Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.
Leuk. Res. 24:255-262(2000)

PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1
Kaoru Inoue, Takashi Kohno, Satoshi Takakura, Yasuhide Hayashi, Hideaki Mizoguchi, Jun Yokota;
Corrigendum to 'Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines' Leukemia Research 24 (2000), 255-262.
Leuk. Res. 25:275-278(2001)

PubMed=14504097; DOI=10.1182/blood-2003-02-0418
Takeshi Taketani, Tomohiko Taki, Kanji Sugita, Yoshiyuki Furuichi, Eiichi Ishii, Ryoji Hanada, Masahiro Tsuchida, Kenichi Sugita, Kohmei Ida, Yasuhide Hayashi;
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy.
Blood 103:1085-1088(2004)

PubMed=14671638; DOI=10.1038/sj.leu.2403236
Hans Gunther Drexler, Hilmar Quentmeier, Roderick A.F. MacLeod;
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.
Leukemia 18:227-232(2004)

Cross-references
Encyclopedic resources Wikidata; Q54955009
Polymorphism and mutation databases Cosmic; 996312
Cosmic; 998747
Cosmic; 1037663
Cosmic; 2393017
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number14