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Cellosaurus H69/VDS (CVCL_AZ78)

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Cell line name H69/VDS
Accession CVCL_AZ78
Resource Identification Initiative To cite this cell line use: H69/VDS (RRID:CVCL_AZ78)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_36373; Vindesine.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1579 (NCI-H69)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
Publications

PubMed=8391305; DOI=10.1038/bjc.1993.289; PMCID=PMC1968300
Sei Ohta, Kazuto Nishio, Sachiyo Kubo, Makoto Nishio, Tohru Ohmori, Terumi Takahashi, Nagahiro Saijo;
Characterisation of a vindesine-resistant human small-cell lung cancer cell line.
Br. J. Cancer 68:74-79(1993)

Cross-references
Cell line databases/resources cancercelllines; CVCL_AZ78
Encyclopedic resources Wikidata; Q38568625
Entry history
Entry creation02-May-2016
Last entry update19-Dec-2024
Version number14