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Cellosaurus SW480/BEVA (CVCL_AU17)

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Cell line name SW480/BEVA
Accession CVCL_AU17
Resource Identification Initiative To cite this cell line use: SW480/BEVA (RRID:CVCL_AU17)
Comments Population: Caucasian.
Selected for resistance to: DrugBank; DB00112; Bevacizumab (Avastin).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Web pages Provider; MD Anderson CCAC; -; https://www.mdanderson.org/content/dam/mdanderson/documents/core-facilities/Characterized%20Cell%20Line%20Core%20Facility/CCLC%20Cell%20Line%20List%20to%20Distribute.pdf
Cross-references
Cell line databases/resources cancercelllines; CVCL_AU17
Encyclopedic resources Wikidata; Q54971157
Entry history
Entry creation02-May-2016
Last entry update10-Apr-2025
Version number17