Cellosaurus cell line RKO/5FUR (CVCL

Cellosaurus RKO/5FUR (CVCL_AU13)

Cross-references
Cell line name	RKO/5FUR
Accession	CVCL_AU13
Resource Identification Initiative	To cite this cell line use: RKO/5FUR (RRID:CVCL_AU13)
Comments	Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU). Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations	Mutation; HGNC; HGNC:173; ACVR2A; Simple; p.Lys437Argfs5 (c.1310delA); dbSNP=rs764719749; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Lys128Serfs35 (c.383delA); ClinVar=VCV000477546; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Leu452Pro (c.1355T>C); ClinVar=VCV000930524; Zygosity=Heterozygous (from parent cell line).
Disease	Colon carcinoma (NCIt: C4910)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0504 (RKO)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Web pages	Provider; MD Anderson CCAC; -; https://www.mdanderson.org/content/dam/mdanderson/documents/core-facilities/Characterized%20Cell%20Line%20Core%20Facility/CCLC%20Cell%20Line%20List%20to%20Distribute.pdf
Cell line databases/resources	cancercelllines; CVCL_AU13
Encyclopedic resources	Wikidata; Q54950559
Entry history
Entry creation	02-May-2016
Last entry update	10-Apr-2025
Version number	14