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Cellosaurus HTh74 clone 7 (CVCL_AT82)

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Cell line name HTh74 clone 7
Synonyms HTh-74 clone7; U-Hth74-clone7
Accession CVCL_AT82
Resource Identification Initiative To cite this cell line use: HTh74 clone 7 (RRID:CVCL_AT82)
Comments Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Cell type: Epithelial cell; CL=CL_0000066.
Sequence variations
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.Leu732fs (c.2195_2202delTGCCCAAC); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Homozygous; Note=In promoter (from parent cell line).
Disease Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6288 (HTh74)
Sex of cell Female
Age at sampling 73Y
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,12
D7S8208,9
D13S31712,13
D16S53911
TH018,9
TPOX11
vWA17,19

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Publications

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Mei Zhao, Daisuke Sano, Curtis R. Pickering, Samar A. Jasser, Ying C. Henderson, Gary L. Clayman, Erich M. Sturgis, Thomas J. Ow, Reuben Lotan, Thomas E. Carey, Peter G. Sacks ...Show all 15 authors... , Jennifer Rubin Grandis, David Sidransky, Nils-Erik Heldin, Jeffrey N. Myers; Show fewer authors
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

Cross-references
Encyclopedic resources Wikidata; Q54896657
Entry history
Entry creation02-May-2016
Last entry update19-Dec-2024
Version number13