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Cellosaurus SW480E (CVCL_AT67)

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Cell line name SW480E
Synonyms SW480 E8; E8; SW480 Epithelial-type clone 8
Accession CVCL_AT67
Resource Identification Initiative To cite this cell line use: SW480E (RRID:CVCL_AT67)
Comments Population: Caucasian.
Doubling time: 32.6 hours (PubMed=1458472).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (PubMed=1458472).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): KCLB=60067

Markers:
AmelogeninX
CSF1PO13,14
D3S135815
D5S81813
D7S8208
D13S31712
FGA24
TH018
TPOX11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=1458472
Naohiro Tomita, Wei Jiang, Hanina Hibshoosh, Dorothy Warburton, Scott M. Kahn, I. Bernard Weinstein;
Isolation and characterization of a highly malignant variant of the SW480 human colon cancer cell line.
Cancer Res. 52:6840-6847(1992)

Patent=US7989001
Untae Kim, Stefan A. Cohen;
Method of separating tumor cells with and without lymphotropic metastatic potential in a human carcinoma.
Patent number US7989001, 02-Aug-2011

Cross-references
Cell line collections (Providers) KCLB; 60067
Cell line databases/resources cancercelllines; CVCL_AT67
Encyclopedic resources Wikidata; Q54971172
Entry history
Entry creation02-May-2016
Last entry update27-Nov-2025
Version number17