Cellosaurus cell line COG-LL-402h (CVCL

Cellosaurus COG-LL-402h (CVCL_AQ49)

[Text version]

Cell line name

COG-LL-402h

Accession

CVCL_AQ49

Resource Identification Initiative

To cite this cell line use: COG-LL-402h (RRID:CVCL_AQ49)

Comments

Omics: Proteomics; Quantitative.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.

Sequence variations

Gene fusion; HGNC; HGNC:8632; PBX1 + HGNC; HGNC:11633; TCF3; Name(s)=TCF3-PBX1, E2A-PBX1 (PubMed=35354797).

Disease

Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

Category

Cancer cell line

STR profile

Source(s): COG

Markers:

Amelogenin	X,Y
CSF1PO	10,14
D2S1338	19,22
D3S1358	14,16
D5S818	11
D7S820	10
D8S1179	14,15
D13S317	10,11
D16S539	12,13
D18S51	16,18
D19S433	13,15
D21S11	28
FGA	24
TH01	7,8
TPOX	8,11
vWA	14,17

Web pages

Provider; CCR; -; https://www.cccells.org/PDF_Files/LL-PDX/COG-LL-402h.pdf
Provider; CCR; -; https://www.cccells.org/tables/Lymphoid.php

Publications

PubMed=26080839; DOI=10.1158/1078-0432.CCR-15-0114; PMCID=PMC4681691
Connor P. Hall, Charles Patrick Reynolds, Min H. Kang;
Modulation of glucocorticoid resistance in pediatric T-cell acute lymphoblastic leukemia by increasing BIM expression with the PI3K/mTOR inhibitor BEZ235.
Clin. Cancer Res. 22:621-632(2016)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5; PMCID=PMC8967900
Isabelle Rose Leo, Luay Aswad, Matthias Stahl, Elena Kunold, Frederik Post, Tom Erkers, Nona Struyf, Georgios Mermelekas, Rubin Narayan Joshi, Eva Gracia-Villacampa, Paivi Ostling ...Show all 17 authors... , Olli-Pekka Kallioniemi, Katja Pokrovskaja Tamm, Ioannis Siavelis, Janne Lehtio, Mattias Vesterlund, Rozbeh Jafari; Show fewer authors
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cross-references

Encyclopedic resources

Wikidata; Q54813977

Gene expression databases

GEO; GSM5137756

Proteomic databases

PRIDE; PXD023662

Entry history

Entry creation

02-May-2016

Last entry update

10-Apr-2025

Version number