Cellosaurus cell line HCEC 2CT (CVCL

Cellosaurus HCEC 2CT (CVCL_AQ47)

Cross-references
Cell line name	HCEC 2CT
Synonyms	Human Colonic Epithelial Cells 2 transduced with CDK4 and Telomerase; 2CT
Accession	CVCL_AQ47
Resource Identification Initiative	To cite this cell line use: HCEC 2CT (RRID:CVCL_AQ47)
Comments	Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	52Y
Category	Telomerase immortalized cell line
Publications	PubMed=19962984; DOI=10.1053/j.gastro.2009.11.052 Andres I. Roig, Ugur Eskiocak, Suzie K. Hight, Sang Bum Kim, Oliver Delgado, Rhonda F. Souza, Stuart J. Spechler, Woodring Erik Wright, Jerry W. Shay; Immortalized epithelial cells derived from human colon biopsies express stem cell markers and differentiate in vitro. Gastroenterology 138:1012-1021.e215(2010) PubMed=21527559; DOI=10.1158/0008-5472.CAN-11-0794; PMCID=PMC3326261 Ugur Eskiocak, Sang Bum Kim, Peter Ly, Andres I. Roig, Sebastian Biglione, Kakajan Komurov, Crystal Cornelius, Woodring Erik Wright, Michael A. White, Jerry W. Shay; Functional parsing of driver mutations in the colorectal cancer genome reveals numerous suppressors of anchorage-independent growth. Cancer Res. 71:4359-4365(2011)
Encyclopedic resources	Wikidata; Q54881865
Experimental variables resources	EFO; EFO_0009499
Entry history
Entry creation	02-May-2016
Last entry update	19-Dec-2024
Version number	8