Cellosaurus cell line HCEC 2CT (CVCL

Cross-references
Cell line name	HCEC 2CT
Synonyms	Human Colonic Epithelial Cells 2 transduced with CDK4 and Telomerase; 2CT
Accession	CVCL_AQ47
Resource Identification Initiative	To cite this cell line use: HCEC 2CT (RRID:CVCL_AQ47)
Comments	Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	52Y
Category	Telomerase immortalized cell line
Publications	PubMed=19962984; DOI=10.1053/j.gastro.2009.11.052 Roig A.I., Eskiocak U., Hight S.K., Kim S.B., Delgado O., Souza R.F., Spechler S.J., Wright W.E., Shay J.W. Immortalized epithelial cells derived from human colon biopsies express stem cell markers and differentiate in vitro. Gastroenterology 138:1012-1021.e215(2010) PubMed=21527559; DOI=10.1158/0008-5472.CAN-11-0794; PMCID=PMC3326261 Eskiocak U., Kim S.B., Ly P., Roig A.I., Biglione S., Komurov K., Cornelius C., Wright W.E., White M.A., Shay J.W. Functional parsing of driver mutations in the colorectal cancer genome reveals numerous suppressors of anchorage-independent growth. Cancer Res. 71:4359-4365(2011)
Encyclopedic resources	Wikidata; Q54881865
Experimental variables resources	EFO; EFO_0009499
Entry history
Entry creation	02-May-2016
Last entry update	19-Dec-2024
Version number	8