Cellosaurus logo
expasy logo

Cellosaurus CHLA-06-ATRT (CVCL_AQ42)

[Text version]
Cell line name CHLA-06-ATRT
Synonyms CHLA06ATRT; CHLA-06
Accession CVCL_AQ42
Resource Identification Initiative To cite this cell line use: CHLA-06-ATRT (RRID:CVCL_AQ42)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His178Asp (c.532C>G); ClinVar=VCV000482223; Zygosity=Unspecified (DepMap=ACH-001028).
Disease Atypical teratoid/rhabdoid tumor (NCIt: C6906)
Atypical teratoid rhabdoid tumor (ORDO: Orphanet_99966)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 4M
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3038

Markers:
AmelogeninX
CSF1PO11
D5S81811
D7S82011,13
D13S31713,14
D16S53911,12
TH017
TPOX12
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=24300787; DOI=10.1158/1078-0432.CCR-13-2053; PMCID=PMC3962776
Anat Erdreich-Epstein, Nathan Robison, Xiu-Hai Ren, Hong Zhou, Jing-Ying Xu, Tom B. Davidson, Mathew Schur, Floyd Harry Gilles, Ling-Yun Ji, Jemily Malvar, Gregory M. Shackleford ...Show all 19 authors... , Ashley Sloane Margol, Mark D. Krieger, Alexander Russell Judkins, David T.W. Jones, Stefan Michael Pfister, Marcel Kool, Richard Sposto, Shahab Asgharzadeh; Show fewer authors
PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors and gliomas.
Clin. Cancer Res. 20:827-836(2014)

PubMed=25211508; DOI=10.1002/jcb.24976; PMCID=PMC10656279
Jing-Ying Xu, Ashley Sloane Margol, Shahab Asgharzadeh, Anat Erdreich-Epstein;
Pediatric brain tumor cell lines.
J. Cell. Biochem. 116:218-224(2015)

PubMed=25246426; DOI=10.1093/neuonc/nou229; PMCID=PMC4483069
Madhavi Chakravadhanula, Chris N. Hampton, Parth Chodavadia, Victor Ozols, Li Zhou, Daniel Catchpoole, Jing-Ying Xu, Anat Erdreich-Epstein, Ratan D. Bhardwaj;
Wnt pathway in atypical teratoid rhabdoid tumors.
Neuro-oncol. 17:526-535(2015)

PubMed=25638158; DOI=10.18632/oncotarget.3078; PMCID=PMC4413645
Melanie F. Weingart, Jacquelyn J. Roth, Marianne Hutt-Cabezas, Tracy M. Busse, Harpreet Kaur, Antoinette Price, Rachael Maynard, Jeffrey Rubens, Isabella C. Taylor, Xing-Gang Mao, Jing-Ying Xu ...Show all 19 authors... , Yasumichi Kuwahara, Sariah J. Allen, Anat Erdreich-Epstein, Bernard E. Weissman, Brent A. Orr, Charles George Eberhart, Jaclyn A. Biegel, Eric Hutton Raabe; Show fewer authors
Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target.
Oncotarget 6:3165-3177(2015)

Cross-references
Cell line collections (Providers) ATCC; CRL-3038
Cell line databases/resources cancercelllines; CVCL_AQ42
Cell_Model_Passport; SIDM01550
DepMap; ACH-001028
Encyclopedic resources Wikidata; Q54812146
Entry history
Entry creation02-May-2016
Last entry update10-Apr-2025
Version number15