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Cellosaurus HEK 293 STF (CVCL_AQ26)

[Text version]
Cell line name HEK 293 STF
Synonyms STF; Super TOP-FLASH; SuperTopFlash
Accession CVCL_AQ26
Resource Identification Initiative To cite this cell line use: HEK 293 STF (RRID:CVCL_AQ26)
Comments Characteristics: Responds to activation of the canonical Wnt signaling pathway by increasing expression of firefly luciferase. Luciferase reporter gene expression is under the control of a promoter with 7 LEF/TCF binding sites (PubMed=15035989).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Children:
CVCL_C6NQ (STF3a)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO11,12
D5S8188,9
D7S82011,12
D13S31712,14
D16S5399
TH017,9.3
TPOX11
vWA16,19

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Publications

PubMed=15035989; DOI=10.1016/S0092-8674(04)00216-8
Xu Q., Wang Y.-S., Dabdoub A., Smallwood P.M., Williams J., Woods C., Kelley M.W., Jiang L., Tasman W., Zhang K., Nathans J.
Vascular development in the retina and inner ear: control by norrin and frizzled-4, a high-affinity ligand-receptor pair.
Cell 116:883-895(2004)

Cross-references
Cell line collections (Providers) ATCC; CRL-3249
Kerafast; EJH014
Encyclopedic resources Wikidata; Q54882278
Entry history
Entry creation02-May-2016
Last entry update05-Oct-2023
Version number11