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Cellosaurus COG-N-415 (CVCL_AQ23)

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Cell line name COG-N-415
Synonyms COGN415
Accession CVCL_AQ23
Resource Identification Initiative To cite this cell line use: COG-N-415 (RRID:CVCL_AQ23)
Comments Doubling time: 50 hours (COG).
Omics: Genomics; ChIP-seq; H3K27ac.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K4me1.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Genomics; Chromatin accessibility; ATAC-seq.
Omics: Transcriptomics; RNAseq.
Sequence variations
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling 2Y
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX
CSF1PO10,11
D2S133819,21
D3S135814,15
D5S81811
D7S8209,10
D8S117911,13,14
D13S31711,12
D16S53911
D18S5112,15
D19S43314,15
D21S1128,29
FGA19,22
TH017,8
TPOX11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=24792489; DOI=10.1007/s11060-014-1456-8
Ahsan S. Farooqi, Rebecca A. Dagg, L. Mi Rim Choi, Jerry W. Shay, Charles Patrick Reynolds, Loretta M.S. Lau;
Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.
J. Neurooncol. 119:17-26(2014)

PubMed=28340497; DOI=10.1002/ijc.30706
Lluis Lopez-Barcons, Barry J. Maurer, Min H. Kang, Charles Patrick Reynolds;
P450 inhibitor ketoconazole increased the intratumor drug levels and antitumor activity of fenretinide in human neuroblastoma xenograft models.
Int. J. Cancer 141:405-413(2017)

PubMed=28350380; DOI=10.1038/sdata.2017.33; PMCID=PMC5369315
Jo Lynne Harenza, Maura A. Diamond, Rebecca N. Adams, Michael M. Song, Heather L. Davidson, Lori S. Hart, Maiah H. Dent, Paolo Fortina, Charles Patrick Reynolds, John Matthew Maris;
Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.
Sci. Data 4:170033.1-170033.8(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_AQ23
Encyclopedic resources Wikidata; Q54814023
Gene expression databases GEO; GSM2371224
GEO; GSM4104571
GEO; GSM4104572
GEO; GSM4104624
GEO; GSM4104625
GEO; GSM4105303
GEO; GSM4105304
GEO; GSM4105305
GEO; GSM4105306
GEO; GSM4105307
Entry history
Entry creation02-May-2016
Last entry update10-Apr-2025
Version number14