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Cellosaurus FAP 6888-1 (CVCL_A9Z8)

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Cell line name FAP 6888-1
Synonyms FAP6888-1; FAP6888
Accession CVCL_A9Z8
Resource Identification Initiative To cite this cell line use: FAP 6888-1 (RRID:CVCL_A9Z8)
Comments From: Center for Regenerative Medicine; Boston; USA.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Glu1538Ilefs*5 (c.4612_4613delAG) (P1542X); ClinVar=VCV000000823; Zygosity=Unspecified (PubMed=30024920).
Disease Familial adenomatous polyposis (NCIt: C3339)
Familial adenomatous polyposis (ORDO: Orphanet_733)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_CY45 (GM06888)
Sex of cell Male
Age at sampling 16Y
Category Induced pluripotent stem cell
Web pages Provider; CReM; 673; https://stemcellbank.bu.edu/Catalog/Item/Details/673
Publications

PubMed=30024920; DOI=10.1371/journal.pone.0200657; PMCID=PMC6053155
Cesar A. Sommer, Amalia Capilla, Francisco Javier Molina-Estevez, Andreia Gianotti-Sommer, Nicholas J. Skvir, Ignacio Caballero, Sanjib Chowdhury, Gustavo Mostoslavsky;
Modeling APC mutagenesis and familial adenomatous polyposis using human iPS cells.
PLoS ONE 13:e0200657.1-e0200657.21(2018)

Cross-references
Encyclopedic resources Wikidata; Q102113809
Entry history
Entry creation29-Oct-2020
Last entry update10-Apr-2025
Version number9