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Cellosaurus HHT4 (CVCL_A9Z1)

[Text version]
Cell line name HHT4
Synonyms HHT-4
Accession CVCL_A9Z1
Resource Identification Initiative To cite this cell line use: HHT4 (RRID:CVCL_A9Z1)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Adult
Category Telomerase immortalized cell line
Publications

PubMed=17404395; DOI=10.1093/carcin/bgm075
Anuradha S. Budhu, Y. Chen, Jin Woo Kim, Marshonna Forgues, Kristoffer Valerie, Curtis Craig Harris, Xin-Wei Wang;
Induction of a unique gene expression profile in primary human hepatocytes by hepatitis C virus core, NS3 and NS5A proteins.
Carcinogenesis 28:1552-1560(2007)

PubMed=20017137; DOI=10.1002/ijc.25118; PMCID=PMC2950321
Wei-Dong Jiang, Xin-Wei Wang, Tamar Unger, Marshonna Forgues, Jin Woo Kim, S. Perwez Hussain, Elise Bowman, Elisa A. Spillare, Michael M. Lipsky, Jeanne M. Meck, Luciane R. Cavalli ...Show all 13 authors... , Bassem R. Haddad, Curtis Craig Harris; Show fewer authors
Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line.
Int. J. Cancer 127:1011-1020(2010)

PubMed=32899426; DOI=10.3390/cancers12092510; PMCID=PMC7565451
Dominique Scherer, Marcela Davila-Lopez, Benjamin Goeppert, Sanna Abrahamsson, Rosa Gonzalez Silos, Igor Nova, Katherine Marcelain, Juan Carlos Roa, David Ibberson, Sinan U. Umu, Trine Ballestad Rounge ...Show all 13 authors... , Stephanie Roessler, Justo Lorenzo-Bermejo; Show fewer authors
RNA sequencing of hepatobiliary cancer cell lines: data and applications to mutational and transcriptomic profiling.
Cancers (Basel) 12:2510.1-2510.14(2020)

Cross-references
Encyclopedic resources Wikidata; Q102114125
Entry history
Entry creation29-Oct-2020
Last entry update14-Aug-2025
Version number9