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Cellosaurus MOC-L2 (CVCL_A9X4)

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Cell line name MOC-L2
Synonyms Mouse Oral Carcinoma-Line 2
Accession CVCL_A9X4
Resource Identification Initiative To cite this cell line use: MOC-L2 (RRID:CVCL_A9X4)
Comments Characteristics: Tumorigenic in syngeneic mice.
Doubling time: 20.4 hours (PubMed=30922255).
Genetic integration: Method=Transgenic mouse; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:2676887; Mir211.
Transformant: ChEBI; CHEBI_16907; 4-nitroquinoline N-oxide (4NQO).
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; MGI; MGI:98834; Trp53; Simple; p.Ala156Pro (c.466G>C); Zygosity=Unspecified (PubMed=30922255).
Disease Squamous cell carcinoma of the mouse oral cavity (NCIt: C23049)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 K14-EGFP-miR-211 transgenic.
Sex of cell Sex unspecified
Age at sampling 22-28W
Category Cancer cell line
Publications

PubMed=30922255; DOI=10.1186/s12885-019-5486-7; PMCID=PMC6440159
Yi-Fen Chen, Chung-Ji Liu, Li-Han Lin, Chung-Hsien Chou, Li-Yin Yeh, Shu-Chun Lin, Kuo-Wei Chang;
Establishing of mouse oral carcinoma cell lines derived from transgenic mice and their use as syngeneic tumorigenesis models.
BMC Cancer 19:281.1-281.11(2019)

Cross-references
Cell line collections (Providers) ABM; T8047
BCRC; 60617
Encyclopedic resources Wikidata; Q102114548
Entry history
Entry creation29-Oct-2020
Last entry update10-Apr-2025
Version number8