Cellosaurus cell line CTSC#416 (CVCL

Cellosaurus CTSC#416 (CVCL_A9WR)

[Text version]

Cell line name

CTSC#416

Synonyms

CRC-SC#416; CSC13

Accession

CVCL_A9WR

Resource Identification Initiative

To cite this cell line use: CTSC#416 (RRID:CVCL_A9WR)

Comments

Group: Cancer stem cell line.
From: Sant Andrea Hospital; Rome; Italy.
Microsatellite instability: Instable (MSI-high) (PubMed=33128777).
Derived from site: In situ; Colon, proximal; UBERON=UBERON_0008972.

Sequence variations

Mutation; HGNC; HGNC:6768; SMAD2; Simple; p.Arg462His (c.1385G>A); ClinVar=VCV001308032; Zygosity=Unspecified (PubMed=33128777).
Mutation; HGNC; HGNC:11204; SOX9; Simple; p.Ala481Val (c.1442C>T); Zygosity=Unspecified (PubMed=33128777).

Disease

Colon adenocarcinoma (NCIt: C4349)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

82Y

Category

Cancer cell line

STR profile

Source(s): PubMed=33128777

Markers:

Amelogenin	X,Y
CSF1PO	11,12,13
D5S818	11,14
D7S820	12,13
D13S317	7,12
D16S539	11,14
TH01	6,9.3
TPOX	7
vWA	15,18

Publications

PubMed=26956206; DOI=10.5966/sctm.2015-0214; PMCID=PMC4798739
Maria Laura De Angelis, Ann Zeuner, Eleonora Policicchio, Giorgio Russo, Alessandro Bruselles, Michele Signore, Sara Vitale, Gabriele De Luca, Emanuela Pilozzi, Alessandra Boe, Giorgio Stassi ...Show all 18 authors... , Lucia Ricci-Vitiani, Carla Azzurra Amoreo, Alfredo Pagliuca, Federica Francescangeli, Marco Tartaglia, Ruggero De Maria, Marta Baiocchi; Show fewer authors
Cancer stem cell-based models of colorectal cancer reveal molecular determinants of therapy resistance.
Stem Cells Transl. Med. 5:511-523(2016)

PubMed=27286453; DOI=10.18632/oncotarget.9859; PMCID=PMC5190083
Michele Signore, Mariachiara Buccarelli, Emanuela Pilozzi, Gabriele De Luca, Marianna Cappellari, Maurizio Fanciulli, Frauke Goeman, Elisa Melucci, Mauro Biffoni, Lucia Ricci-Vitiani;
UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response.
Oncotarget 7:44113-44128(2016)

PubMed=33128777; DOI=10.1002/ijc.33370; PMCID=PMC7894552
Paola Visconti, Federica Parodi, Barbara Parodi, Lucia Casarino, Paolo Romano, Mariachiara Buccarelli, Roberto Pallini, Quintino Giorgio D'Alessandris, Andrea Montori, Emanuela Pilozzi, Lucia Ricci-Vitiani;
Short tandem repeat profiling for the authentication of cancer stem-like cells.
Int. J. Cancer 148:1489-1498(2021)

Cross-references

Encyclopedic resources

Wikidata; Q102113744

Entry history

Entry creation

29-Oct-2020

Last entry update

19-Dec-2024

Version number