Cellosaurus cell line FTDP-17-2-I (CVCL

Cross-references
Cell line name	FTDP-17-2-I
Accession	CVCL_A9R4
Resource Identification Initiative	To cite this cell line use: FTDP-17-2-I (RRID:CVCL_A9R4)
Comments	Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:6893; MAPT; Simple; p.Val337Met (c.1009G>A) (V654M, c.1960G>A or V672M, c.2014G>A); ClinVar=VCV000014252; Zygosity=Unspecified (PubMed=26143746).
Disease	Frontotemporal dementia-1 (NCIt: C217087) Behavioral variant of frontotemporal dementia (ORDO: Orphanet_275864)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_EY39 (ND32951)
Sex of cell	Female
Category	Induced pluripotent stem cell
Publications	PubMed=26143746; DOI=10.1016/j.stemcr.2015.06.001; PMCID=PMC4618448 Marc Ehrlich, Anna-Lena Hallmann, Peter Reinhardt, Marcos J. Arauzo-Bravo, Sabrina Korr, Albrecht Ropke, Olympia Ekaterini Psathaki, Petra Ehling, Sven Gunther Meuth, Adrian L. Oblak, Jill R. Murrell ...Show all 17 authors... , Bernardino Ghetti, Holm Zaehres, Hans Robert Scholer, Jared Sterneckert, Tanja Kuhlmann, Gunnar Hargus; Show fewer authors Distinct neurodegenerative changes in an induced pluripotent stem cell model of frontotemporal dementia linked to mutant Tau protein. Stem Cell Reports 5:83-96(2015)
Encyclopedic resources	Wikidata; Q102113860
Entry history
Entry creation	29-Oct-2020
Last entry update	14-Aug-2025
Version number	9