Cellosaurus cell line FFF-022 (CVCL

Cellosaurus FFF-022 (CVCL_A9P7)

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Cell line name

FFF-022

Synonyms

FFF0962009

Accession

CVCL_A9P7

Resource Identification Initiative

To cite this cell line use: FFF-022 (RRID:CVCL_A9P7)

Comments

Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.

Sequence variations

Mutation; HGNC; HGNC:18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Heterozygous (PubMed=22666358).

Disease

Parkinson disease 8, autosomal dominant (NCIt: C198605)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_V157 (ESi061-A)

Sex of cell

Male

Age at sampling

47Y

Category

Finite cell line

Publications

PubMed=22666358; DOI=10.1371/journal.pone.0037467; PMCID=PMC3359730
Daniele Cartelli, Stefano Goldwurm, Francesca Casagrande, Gianni Pezzoli, Graziella Cappelletti;
Microtubule destabilization is shared by genetic and idiopathic Parkinson's disease patient fibroblasts.
PLoS ONE 7:e37467.1-e37467.12(2012)

PubMed=23075850; DOI=10.1038/nature11557; PMCID=PMC3504651
Guang-Hui Liu, Jing Qu, Keiichiro Suzuki, Emmanuel Nivet, Mo Li, Nuria Montserrat, Fei Yi, Xiu-Ling Xu, Sergio Ruiz, Wei-Qi Zhang, Ulrich Wagner ...Show all 23 authors... , Audrey Kim, Bing Ren, Ying Li, April Mary Goebl, Jessica Kim, Rupa Devi Soligalla, Ilir Dubova, James Thompson, John R. Yates 3rd, Concepcion Rodriguez Esteban, Ignacio Sancho-Martinez, Juan Carlos Izpisua Belmonte; Show fewer authors
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2.
Nature 491:603-607(2012)

Cross-references

Encyclopedic resources

Wikidata; Q102113819

Entry history

Entry creation

29-Oct-2020

Last entry update

19-Dec-2024

Version number