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Cellosaurus PT12 (CVCL_A9E6)

[Text version]
Cell line name PT12
Accession CVCL_A9E6
Resource Identification Initiative To cite this cell line use: PT12 (RRID:CVCL_A9E6)
Comments Characteristics: ER/PR-positive and ERBB2-negative. Established from a mouse xenograft.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=22821401; DOI=10.1007/s10549-012-2164-8; PMCID=PMC3818141
Peter Kabos, Jessica Finlay-Schultz, Chun-Ling Li, Enos C. Kline, Christina Finlayson, Joshua Wisell, Christopher A. Manuel, Susan M. Edgerton, J. Chuck Harrell, Anthony David Elias, Carol A. Sartorius;
Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures.
Breast Cancer Res. Treat. 135:415-432(2012)

PubMed=27565181; DOI=10.1158/1541-7786.MCR-16-0167; PMCID=PMC5107172
Nicholas C. D'Amato, Michael A. Gordon, Beatrice Babbs, Nicole S. Spoelstra, Kiel T. Carson Butterfield, Kathleen C. Torkko, Vernon T. Phan, Valerie N. Barton, Thomas J. Rogers, Carol A. Sartorius, Anthony David Elias ...Show all 14 authors... , Jason Gertz, Britta M. Jacobsen, Jennifer K. Richer; Show fewer authors
Cooperative dynamics of AR and ER activity in breast cancer.
Mol. Cancer Res. 14:1054-1067(2016)

PubMed=30317423; DOI=10.1007/s10549-018-4989-2; PMCID=PMC6813790
Anna Astashchanka, Thomas M. Shroka, Britta M. Jacobsen;
Mucin 2 (MUC2) modulates the aggressiveness of breast cancer.
Breast Cancer Res. Treat. 173:289-299(2019)

Cross-references
Encyclopedic resources Wikidata; Q102114788
Entry history
Entry creation29-Oct-2020
Last entry update29-Jun-2023
Version number6