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Cellosaurus PUMC-CRC1 (CVCL_A9DD)

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Cell line name PUMC-CRC1
Synonyms Peking Union Medical College-ColoRectal Cancer 1
Accession CVCL_A9DD
Resource Identification Initiative To cite this cell line use: PUMC-CRC1 (RRID:CVCL_A9DD)
Comments Population: Chinese.
Doubling time: 44 hours (PubMed=34162944).
Microsatellite instability: Stable (MSS) (PubMed=34162944).
Derived from site: In situ; Cecum; UBERON=UBERON_0001153.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1493fs (c.4476_4479delCACGinsACA); Zygosity=Heterozygous (PubMed=34162944).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Heterozygous (PubMed=34162944).
  • Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Val506Glu (c.1517T>C); Zygosity=Homozygous (PubMed=34162944).
Disease Cecum adenocarcinoma (NCIt: C5543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000859; PubMed=34162944

Markers:
AmelogeninX
CSF1PO12
D2S133818,24
D3S135815,16
D5S81811
D6S104311,14
D7S8207,11
D8S117913,15
D12S39117,18
D13S3178,10
D16S53910
D18S5116
D19S43313,13.2
D21S1130,32
FGA20
Penta E17
TH017,9
TPOX8,9
vWA16

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Publications

PubMed=34162944; DOI=10.1038/s41598-021-92491-7; PMCID=PMC8222262
Xiao-Cui Bian, Fang Cao, Xiao-Wan Wang, Yu-Hong Hou, Hai-Tao Zhao, Yu-Qin Liu;
Establishment and characterization of a new human colon cancer cell line, PUMC-CRC1.
Sci. Rep. 11:13122.1-13122.12(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A9DD
CCRID; 1101HUM-PUMC000859
Encyclopedic resources Wikidata; Q108821177
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number7