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Cellosaurus Ecad-231-9 (CVCL_A9BQ)

[Text version]
Cell line name Ecad-231-9
Synonyms Ecad231-9
Accession CVCL_A9BQ
Resource Identification Initiative To cite this cell line use: Ecad-231-9 (RRID:CVCL_A9BQ)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Transfected with: HGNC; 1748; CDH1.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0062 (MDA-MB-231)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=21215101; DOI=10.3760/cma.j.issn.0529-5807.2010.12.011
Yang L.-J., Liu Y.-Q., Gu B., Bian X.-C., Feng H.-L., Yang Z.-L., Liu Y.-Y.
Effect of forced E-cadherin expression on adhesion and proliferation of human breast carcinoma cells.
Zhonghua Bing Li Xue Za Zhi 39:842-847(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A9BQ
CCRID; 1101HUM-PUMC000399
Encyclopedic resources Wikidata; Q108820181
Entry history
Entry creation23-Sep-2021
Last entry update05-Oct-2023
Version number6