Cellosaurus cell line IGR/Cut40 (CVCL

Cross-references
Cell line name	IGR/Cut40
Accession	CVCL_A9AP
Resource Identification Initiative	To cite this cell line use: IGR/Cut40 (RRID:CVCL_A9AP)
Comments	Doubling time: ~28 hours (PubMed=21556589). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (PubMed=21556589).
Disease	Human papillomavirus-independent cervical squamous cell carcinoma (NCIt: C180841) Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=21556589; DOI=10.3892/ijo.6.3.681 Severine Fogel, Jean-Charles Ahomadegbe, Marie-Luce Le Bihan, Michel Barrois, Guy Riou; Characterization of a new p53-mutated and HPV-negative human squamous-cell cervical carcinoma-derived cell-line. Int. J. Oncol. 6:681-686(1995) PubMed=9581783; DOI=10.1006/viro.1998.9086 Severine Fogel, Guy Riou; The early HPV16 proteins can regulate mRNA levels of cell cycle genes in human cervical carcinoma cells by p53-independent mechanisms. Virology 244:97-107(1998)
Cell line databases/resources	cancercelllines; CVCL_A9AP
Encyclopedic resources	Wikidata; Q108820532
Polymorphism and mutation databases	IARC_TP53; 3786
Entry history
Entry creation	23-Sep-2021
Last entry update	19-Dec-2024
Version number	7