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Cellosaurus HOS-SL (CVCL_A9AN)

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Cell line name HOS-SL
Accession CVCL_A9AN
Resource Identification Initiative To cite this cell line use: HOS-SL (RRID:CVCL_A9AN)
Comments Population: Caucasian.
Characteristics: Non-tumorigenic.
Transformant: NCBI_TaxID; 11808; Kirsten murine sarcoma virus (Ki-MSV).
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (PubMed=2531855).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2544 (KHOS-240S)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=2978869
Jean-Claude Ehrhart, Arlette Duthu, Stephen Ullrich, Ettore Appella, Pierre May;
Specific interaction between a subset of the p53 protein family and heat shock proteins hsp72/hsc73 in a human osteosarcoma cell line.
Oncogene 3:595-603(1988)

PubMed=2531855
Joseph W. Romano, Jean-Claude Ehrhart, Arlette Duthu, C.M. Kim, Ettore Appella, Pierre May;
Identification and characterization of a p53 gene mutation in a human osteosarcoma cell line.
Oncogene 4:1483-1488(1989)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A9AN
Encyclopedic resources Wikidata; Q108820494
Polymorphism and mutation databases IARC_TP53; 230
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number6