| Cell line name |
CUi001-A-1 |
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| Synonyms |
WB1-10 WRNKI-Cre18 |
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| Accession |
CVCL_A8ZC |
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| Resource Identification Initiative |
To cite this cell line use: CUi001-A-1 (RRID:CVCL_A8ZC) |
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| Comments |
From: Chiba University; Chiba; Japan.
Population: Japanese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. |
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| Sequence variations |
- Mutation; HGNC; HGNC:12791; WRN; Simple; p.Lys1046fs*14 (c.3139-1G>C) (IVS25-1G>C); ClinVar=VCV000005447; Zygosity=Heterozygous; Note=Splice acceptor mutation (PubMed=34087989).
- Mutation; HGNC; HGNC:12791; WRN; Simple_corrected; p.Lys1046fs*14 (c.3139-1G>C) (IVS25-1G>C); ClinVar=VCV000005447; Zygosity=Heterozygous; Note=By CRISPR/Cas9. Splice acceptor mutation (PubMed=34087989).
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| Disease |
Werner syndrome (NCIt: C3447)
Werner syndrome (ORDO: Orphanet_902) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_A8ZB (CUi001-A) |
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| Sex of cell |
Male |
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| Age at sampling |
52Y |
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| Category |
Induced pluripotent stem cell |
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| STR profile |
Source(s): PubMed=34087989
Markers:| Amelogenin | X,Y |
| CSF1PO | 12 |
| D1S1656 | 17 |
| D2S441 | 11,13 |
| D2S1338 | 19,22 |
| D3S1358 | 15,16 |
| D5S818 | 9,10 |
| D7S820 | 10 |
| D8S1179 | 11,14 |
| D10S1248 | 12,13 |
| D12S391 | 18,20 |
| D13S317 | 10,12 |
| D16S539 | 9,10 |
| D18S51 | 19,20 |
| D19S433 | 14,15.2 |
| D21S11 | 29 |
| D22S1045 | 11,17 |
| DYS391 | 10 |
| FGA | 19,26 |
| SE33 | 17,21 |
| TH01 | 9 |
| TPOX | 11,12 |
| vWA | 14,17 |
Run an STR similarity search on this cell line |
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| Publications | PubMed=34087989; DOI=10.1016/j.scr.2021.102360
Hisaya Kato, Yoshiro Maezawa, Yasuo Ouchi, Naoya Takayama, Masamitsu Sone, Kanako Sone, Aki Takada-Watanabe, Kyoko Tsujimura, Masaya Koshizaka, Sayaka Nagasawa, Hisako Saitoh ...Show all 18 authors... , Manami Ohtaka, Mahito Nakanishi, Hidetoshi Tahara, Akira Shimamoto, Atsushi Iwama, Koji Eto, Koutaro Yokote; Show fewer authors
Generation of disease-specific and CRISPR/Cas9-mediated gene-corrected iPS cells from a patient with adult progeria Werner syndrome.
Stem Cell Res. 53:102360-102360(2021) |
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| Cross-references |
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| Cell line databases/resources |
hPSCreg; CUi001-A-1
|
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| Encyclopedic resources |
Wikidata; Q108820094
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| Entry history |
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| Entry creation | 23-Sep-2021 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 5 |
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