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Cellosaurus immKEB2 (CVCL_A8UX)

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Cell line name immKEB2
Accession CVCL_A8UX
Resource Identification Initiative To cite this cell line use: immKEB2 (RRID:CVCL_A8UX)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88174; Bmi1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Disease Epidermolysis bullosa dystrophica (NCIt: C84691)
Dystrophic epidermolysis bullosa (ORDO: Orphanet_303)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A8UW ! immFEB2
Sex of cell Male
Age at sampling 16Y
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=33916959

Markers:
AmelogeninX,Y
CSF1PO10,11
D1S165616,18.3
D2S44114,15
D3S135816,17
D5S81811
D7S82011,13
D8S117913,14
D10S124815
D12S39118,22
D13S3178
D16S53911,12
D18S5113,16
D21S1129
D22S104511,15
FGA22,24
SE3314,19
TH019.3
TPOX8,9
vWA15,17

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Publications

PubMed=33916959; DOI=10.3390/ijms22083809; PMCID=PMC8067634
Nadezhda A. Evtushenko, Arkadii K. Beilin, Erdem B. Dashinimaev, Rustam H. Ziganshin, Anastasiya V. Kosykh, Maxim M. Perfilov, Alexandra L. Rippa, Elena V. Alpeeva, Andrey Valentinovich Vasiliev, Ekaterina A. Vorotelyak, Nadya G. Gurskaya;
hTERT-driven immortalization of RDEB fibroblast and keratinocyte cell lines followed by Cre-mediated transgene elimination.
Int. J. Mol. Sci. 22:3809.1-3809.30(2021)

Cross-references
Encyclopedic resources Wikidata; Q108820543
Entry history
Entry creation23-Sep-2021
Last entry update14-Aug-2025
Version number7