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Cellosaurus LCSBi005-A (CVCL_A8MB)

[Text version]
Cell line name LCSBi005-A
Synonyms ND29542-LRRK2/PARK8-G2019S-clone 3; ND29542-LRRK2-clone 3; ND29542-clone 3; ND29542-3
Accession CVCL_A8MB
Resource Identification Initiative To cite this cell line use: LCSBi005-A (RRID:CVCL_A8MB)
Comments From: Luxembourg Centre for Systems Biomedicine; Belvaux; Luxembourg.
Population: Caucasian.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Heterozygous (PubMed=34736041).
Disease Parkinson disease 8, autosomal dominant (NCIt: C198605)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_DD52 (ND29542)
Sex of cell Male
Age at sampling 57Y
Category Transformed cell line
Publications

PubMed=34736041; DOI=10.1016/j.scr.2021.102569
Novak G., Finkbeiner S., Skibinski G., Skupin A.
Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson's patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006).
Stem Cell Res. 57:102569-102569(2021)

Cross-references
Cell line databases/resources hPSCreg; LCSBi005-A
Encyclopedic resources Wikidata; Q108820775
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number4