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Cellosaurus HeLa-LTRHIV-1-Luc (CVCL_A8JX)

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Cell line name HeLa-LTRHIV-1-Luc
Synonyms HeLa LTRHIV-1-Luc; HeLa LTR HIV-1-Luc; HeLa LTRHIV-1wt-Luc
Accession CVCL_A8JX
Resource Identification Initiative To cite this cell line use: HeLa-LTRHIV-1-Luc (RRID:CVCL_A8JX)
Comments Population: African American.
Characteristics: The expression of the luciferase reporter gene is under the control of the HIV-1 isolate BRU promoter (LTR from -454 to +338) (PubMed=17245432).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=17245432; DOI=10.1038/sj.emboj.7601517
du Chene I., Basyuk E., Lin Y.-L., Triboulet R., Knezevich A., Chable-Bessia C., Mettling C., Baillat V., Reynes J., Corbeau P., Bertrand E., Marcello A., Emiliani S., Kiernan R., Benkirane M.
Suv39H1 and HP1gamma are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency.
EMBO J. 26:424-435(2007)

Anatomy/cell type resources BTO; BTO:0005038
Encyclopedic resources Wikidata; Q108820456
Entry history
Entry creation23-Sep-2021
Last entry update05-Oct-2023
Version number6