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Cellosaurus SBKMS-KS1 (CVCL_A8HX)

[Text version]
Cell line name SBKMS-KS1
Synonyms SBKMSKS1; SBSR-AKS
Accession CVCL_A8HX
Resource Identification Initiative To cite this cell line use: SBKMS-KS1 (RRID:CVCL_A8HX)
Comments Derived from site: Metastatic; Groin; UBERON=UBERON_0008337.
Sequence variations
  • Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 1 fusion (Ex7/Ex6) (PubMed=19289832).
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 17Y
Category Cancer cell line
Publications

PubMed=19289832; DOI=10.1073/pnas.0810759106; PMCID=PMC2656557
Gunther H.S. Richter, Stephanie Plehm, Annette Fasan, Sabine Rossler, Rebekka Unland, Idriss M. Bennani-Baiti, Marc Hotfilder, Diana Lowel, Irene von Luettichau, Ilona Mossbrugger, Leticia Quintanilla-Martinez de Fend ...Show all 15 authors... , Heinrich Kovar, Martin S. Staege, Carsten Muller-Tidow, Stefan Burdach; Show fewer authors
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation.
Proc. Natl. Acad. Sci. U.S.A. 106:5324-5329(2009)

PubMed=22080479; DOI=10.1158/1541-7786.MCR-11-0524
Thomas Georg Philipp Grunewald, Isabel Diebold, Irene Esposito, Stephanie Plehm, Kristina Hauer, Uwe Thiel, Patricia da Silva-Buttkus, Frauke Neff, Rebekka Unland, Carsten Muller-Tidow, Colette Zobywalski ...Show all 20 authors... , Katharina Lohrig, Urs Lewandrowski, Albert Sickmann, Olivia Prazeres da Costa, Agnes Gorlach, Andrea Cossarizza, Elke Butt, Gunther H.S. Richter, Stefan Burdach; Show fewer authors
STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors.
Mol. Cancer Res. 10:52-65(2012)

DOI=10.5282/edoc.27750
Martin Franz Orth;
Systematic multi-omics profiling of Ewing sarcoma cell lines.
Thesis PhD (2021); Ludwig Maximilians University of Munich; Munich; Germany

Cross-references
Encyclopedic resources Wikidata; Q107116850
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number5