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Cellosaurus NUC12N2 (CVCL_A8GI)

[Text version]
Cell line name NUC12N2
Accession CVCL_A8GI
Resource Identification Initiative To cite this cell line use: NUC12N2 (RRID:CVCL_A8GI)
Comments Population: Japanese.
Transfected with: HGNC; 16412; NLRC4 (with p.Leu152_Ala1024del, CARD domain, C12N2 construct).
Transfected with: HGNC; 5331; NOD2 (with p.Met1_Ala216del, NACHT+LRR domains, C12N2 construct).
Derived from site: Metastatic; Paragastric lymph node; UBERON=UBERON_8480059.
Disease Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3082 (NUGC-4)
Sex of cell Female
Age at sampling 35Y
Category Cancer cell line

PubMed=16964285; DOI=10.1038/sj.onc.1209965
Hasegawa M., Kawase K., Inohara N., Imamura R., Yeh W.-C., Kinoshita T., Suda T.
Mechanism of ASC-mediated apoptosis: bid-dependent apoptosis in type II cells.
Oncogene 26:1748-1756(2007)

PubMed=20500518; DOI=10.1111/j.1349-7006.2010.01610.x
Motani K., Kawase K., Imamura R., Kinoshita T., Kushiyama H., Suda T.
Activation of ASC induces apoptosis or necrosis, depending on the cell type, and causes tumor eradication.
Cancer Sci. 101:1822-1827(2010)

Encyclopedic resources Wikidata; Q107116596
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number4