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Cellosaurus NUC12N2 (CVCL_A8GI)

[Text version]
Cell line name NUC12N2
Accession CVCL_A8GI
Resource Identification Initiative To cite this cell line use: NUC12N2 (RRID:CVCL_A8GI)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:16412; NLRC4 (Note=With p.Leu152_Ala1024del, CARD domain, C12N2 construct).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5331; NOD2 (Note=With p.Met1_Ala216del, NACHT+LRR domains, C12N2 construct).
Derived from site: Metastatic; Paragastric lymph node; UBERON=UBERON_8480059.
Disease Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3082 (NUGC-4)
Sex of cell Female
Age at sampling 35Y
Category Cancer cell line
Publications

PubMed=16964285; DOI=10.1038/sj.onc.1209965
Mizuho Hasegawa, Kouji Kawase, Naohiro Inohara, Ryu Imamura, Wen-Chen Yeh, Takeshi Kinoshita, Takashi Suda;
Mechanism of ASC-mediated apoptosis: bid-dependent apoptosis in type II cells.
Oncogene 26:1748-1756(2007)

PubMed=20500518; DOI=10.1111/j.1349-7006.2010.01610.x; PMCID=PMC11159384
Kou Motani, Kouji Kawase, Ryu Imamura, Takeshi Kinoshita, Hiroko Kushiyama, Takashi Suda;
Activation of ASC induces apoptosis or necrosis, depending on the cell type, and causes tumor eradication.
Cancer Sci. 101:1822-1827(2010)

Cross-references
Encyclopedic resources Wikidata; Q107116596
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number6